Detection of Single-base Mutation by Affinity Capillary Electrophoresis in a Pdms-glass Hybrid Microdevice
نویسندگان
چکیده
An extremely rapid on-chip separation of DNA from its single-base substituted mutant is described. By using affinity capillary electrophoresis (ACE) in a poly(dimethylsiloxane) (PDMS)-glass hybrid microdevice, we achieved the separation within 5 s.
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